Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique

Click here for a simple search.
[feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
 
 

A. R., Mohd Farhan and K. Y., Pin and M. S., Zamree and Luqman Chuah, Abdullah and Nazira, Mahmud (2015) Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique. Pertanika Journal of Tropical Agricultural Science, 38 (2). pp. 259-270. ISSN 1511-3701 (Print); 2231-8542 (Online)

[img] PDF
Restricted to Repository staff only

973Kb
[img]
Preview
PDF - Published Version
39Kb

Official URL: http://www.pertanika.upm.edu.my/Pertanika%20PAPERS...

Abstract

Orthosiphon stamineus is one of the popular medicinal plants in Southeast Asia. O. stamineus leaves are used in numerous applications related to medicinal purposes and are believed to cure certain health conditions such as hypertension, gout and fever. The aim of this study was to investigate the effect of three parameters involved in extraction process including extraction temperature, extraction duration and solvent to solid ratio on extraction yield, antioxidant activity and referral markers of O. stamineus leaves. The optimisation of extraction processes was evaluated with the aid of Design-Expert software using response surface methodology (RSM). The optimum extraction parameter for O. stamineus leaves were recorded at the extraction temperature of 60°C, 30:1 (ml:g) solvent to solid ratio and 6 hours extraction duration with 30Wt% extract, 67 and 1 mg/L concentration of Rosmarinic acid and Sinensetin, respectively. Antioxidant activity for optimized extract is 96.56% and 91.51% of SOD and DPPH method, respectively.

Item Type:Article
Uncontrolled Keywords:Optimization process, extraction parameter, antioxidant activity, response surface methodology,O. stamineus
Subjects:Q Science > Q Science (General)
Divisions:Faculty of Industrial Sciences And Technology
ID Code:11334
Deposited By: Mrs. Neng Sury Sulaiman
Deposited On:01 Dec 2015 15:31
Last Modified:18 Dec 2015 14:53

Repository Staff Only: item control page

 

 

 

 

 

 

Introduction

An Institutional Repository is an online focus for collecting, preserving, and disseminating any University publication in the digital form for the intellectual sharing.
The UMP Institutional Repository (UMP IR) provides access of University publication such as journal article, conference paper, research paper, thesis and dissertations.


Any Enquiries

Please email or call Knowledge Management staff:-

Pn. Noorul Farina (09-424 5605) OR
Cik Ratna Wilis Haryati (09-424 5612)

Any correspondence concerning this specific repository should be sent to umplibrary@ump.edu.my