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Therapeutic Potential of N-Acetylcysteine for Wound Healing, Acute Bronchiolitis, and Congenital Heart Defects

Almatar, Manaf and Batool, Tahira and Makky, Essam A. (2016) Therapeutic Potential of N-Acetylcysteine for Wound Healing, Acute Bronchiolitis, and Congenital Heart Defects. Current Drug Metabolism, 17 (2). pp. 156-167. ISSN 1875-5453

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Abstract

Wound healing is a composite and vital process in which devitalized tissue layers and cellular structures repair themselves. Bronchiolitis is generally prompted by respiratory syncytial virus or human metapneumovirus; this condition is an acute inflammatory injury of bronchioles. Heart problems that develop before birth are known as congenital heart defects (CHDs), and pregestational diabetes is considered a major predisposing factor of CHDs. N-Acetylcysteine (NAC) is a transformed kind of amino acid cysteine which restores the intracellular levels of the natural antioxidant glutathione when taken internally, thereby assisting the cells’ ability to diminish the damaging effects of reactive oxygen species (ROS).

Item Type: Article
Uncontrolled Keywords: N-acetylcysteine, therapy, mechanism, wound healing, acute bronchiolitis, congenital heart defects
Subjects: R Medicine > RS Pharmacy and materia medica
Faculty/Division: Centre of Excellence: Centre of Excellence for Advanced Research in Fluid Flow
Faculty of Industrial Sciences And Technology
Depositing User: Dr. Essam A. Makky
Date Deposited: 27 Jun 2016 02:16
Last Modified: 10 Jan 2018 05:57
URI: http://umpir.ump.edu.my/id/eprint/13543
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