Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells

Siti Nursyahirah, Ahmad Latfi and Fahmi, Samsuri (2017) Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells. In: 6th IEEE International Conference on Control System, Computing and Engineering (ICCSCE 2016) , 25-27 November 2016 , PARK ROYAL Penang Resort, Penang; Malaysia. pp. 79-84.. ISBN 978-150901178-0

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Abstract

Researchers nowadays prefer biochip technology platform as a medium for conducting the analysis of biological cells where appropriate manipulation techniques like trapping, screening and sorting in a few seconds are required to perform biological cells analysis. Non-uniform AC electric field is required for dielectrophoresis force (DEP) to implement manipulation technique, where the non-uniform AC is generated by microelectrodes designed. The current design has a limitation in term of electric field distribution pattern generated. Thus, ring microarray microelectrode pattern was designed and simulated using COMSOL Multiphysics 4.4 software for implementing one of the main objectives of this study, which is to investigate the electric field distribution resulting from the microelectrodes designed. To optimize the generated DEP force for manipulating biological cells, electric field simulation is very important. The electric field simulation performed by altering some microelectrode geometric design parameters such as the microelectrodes length and the distance between the microelectrodes and the microcavity. The simulation has been shown in this paper. This is intended to simulate the effect of an electric field that results when there are any changes to the geometric design of microelectrodes. Based on the simulation that has been done, the results show the distance between the microelectrodes and microcavity provide more impact in electric field distribution strength compared to the change of the microelectrodes size.

Item Type: Conference or Workshop Item (Speech)
Additional Information: Indexed by Scopus
Uncontrolled Keywords: Biochip; Dielectrophoresis (DEP); Microelectrode design
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering
Faculty/Division: Faculty of Electrical & Electronic Engineering
Depositing User: Mrs. Neng Sury Sulaiman
Date Deposited: 18 Jul 2018 06:52
Last Modified: 18 Jul 2018 06:52
URI: http://umpir.ump.edu.my/id/eprint/18226
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