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Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro

Nadiah, Abu and M. Nadeem, Akhtar and Yeap, Swee Keong and Lim, Kian Lam and Ho, Wan Yong and Aimi Jamil, Zulfadli and Abdul Rahman, Omar and Mohd Roslan, Sulaiman and Mohd Puad, Abdullah and Noorjahan Banu, Alitheen (2014) Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro. PLoS ONE, 9 (10). pp. 1-12. ISSN 1932-6203

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Abstract

The kava-kava plant (Piper methsyticum) is traditionally known as the pacific elixir by the pacific islanders for its role in a wide range of biological activities. The extract of the roots of this plant contains a variety of interesting molecules including Flavokawain A and this molecule is known to have anti-cancer properties. Breast cancer is still one of the leading diagnosed cancers in women today. The metastatic process is also very pertinent in the progression of tumorigenesis.

Item Type: Article
Uncontrolled Keywords: Antineoplastic agent; Caspase 8; Caspase 9; Flavokawain A; Plant extract
Subjects: Q Science > Q Science (General)
Faculty/Division: Faculty of Industrial Sciences And Technology
Depositing User: Mrs. Neng Sury Sulaiman
Date Deposited: 18 Jul 2019 02:37
Last Modified: 18 Jul 2019 02:37
URI: http://umpir.ump.edu.my/id/eprint/25416
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