Tabassum, Shabana and Norhayati, Rosli and Arief Ichwan, Solachuddin Jauhari and Mishrad, Puranjan (2021) Thymoquinone and its pharmacological perspective: A review. Pharmacological Research - Modern Chinese Medicine, 1 (100020). pp. 1-10. ISSN 2667-1425. (Published)
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Pharmacological Research - TQ and Its Pharmacological Perspective A Review.pdf Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (1MB) | Preview |
Abstract
Thymoquinone (TQ) a plant-derived dietary of Nigella sativa, is a well-known traditionally and clinically used natural medicine. The diverse pharmacological properties of TQ have been identified including antimicrobial, antihistamine, antioxidant effects, immunomodulator, and anticancer activities. In this review, investigations regarding the effects of TQ in oxidative stress, immunomodulation, and various type of cancer have been reviewed based on the available relevant literature. TQ-based induction of the immune system by modulating different inflammatory mediators i.e., cytokines, leukins, interleukins, interferons, and other immune cells have been reviewed here. Several studies signified remarkable anticancer potentials of TQ depending upon its concentration and type of cancer cell. Conclusively, understanding pharmacological activities of TQ its molecular mechanism could help researchers to develop a potent analog of well-established chemotherapeutic drugs in clinical trials.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Nigella sativa; Thymoquinone; Antioxidant; Immunomodulatory; Anticancer |
| Subjects: | Q Science > QA Mathematics R Medicine > RC Internal medicine |
| Faculty/Division: | Center for Mathematical Science Institute of Postgraduate Studies |
| Depositing User: | Dr. Norhayati Rosli |
| Date Deposited: | 17 Jun 2022 03:55 |
| Last Modified: | 17 Jun 2022 03:55 |
| URI: | http://umpir.ump.edu.my/id/eprint/32907 |
| Download Statistic: | View Download Statistics |
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