Thymoquinone and its pharmacological perspective: A review

Tabassum, Shabana and Norhayati, Rosli and Arief Ichwan, Solachuddin Jauhari and Mishrad, Puranjan (2021) Thymoquinone and its pharmacological perspective: A review. Pharmacological Research - Modern Chinese Medicine, 1 (100020). pp. 1-10. ISSN 2667-1425. (Published)

Pharmacological Research - TQ and Its Pharmacological Perspective A Review.pdf
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (1MB) | Preview


Thymoquinone (TQ) a plant-derived dietary of Nigella sativa, is a well-known traditionally and clinically used natural medicine. The diverse pharmacological properties of TQ have been identified including antimicrobial, antihistamine, antioxidant effects, immunomodulator, and anticancer activities. In this review, investigations regarding the effects of TQ in oxidative stress, immunomodulation, and various type of cancer have been reviewed based on the available relevant literature. TQ-based induction of the immune system by modulating different inflammatory mediators i.e., cytokines, leukins, interleukins, interferons, and other immune cells have been reviewed here. Several studies signified remarkable anticancer potentials of TQ depending upon its concentration and type of cancer cell. Conclusively, understanding pharmacological activities of TQ its molecular mechanism could help researchers to develop a potent analog of well-established chemotherapeutic drugs in clinical trials.

Item Type: Article
Uncontrolled Keywords: Nigella sativa; Thymoquinone; Antioxidant; Immunomodulatory; Anticancer
Subjects: Q Science > QA Mathematics
R Medicine > RC Internal medicine
Faculty/Division: Center for Mathematical Science
Institute of Postgraduate Studies
Depositing User: Dr. Norhayati Rosli
Date Deposited: 17 Jun 2022 03:55
Last Modified: 17 Jun 2022 03:55
Download Statistic: View Download Statistics

Actions (login required)

View Item View Item