Isolation and characterization of alkaloids from Passiflora feotida for potential of antidepressant compounds

Hazrulrizawati, Abd Hamid and Mohd Hairul, Ab. Rahim and Aizi Nor Mazila, Ramli and Mashitah, Mohd Yusoff and Ahmad Faizal, Abdull Razis (2017) Isolation and characterization of alkaloids from Passiflora feotida for potential of antidepressant compounds. , [Research Book Profile: Research Report] (Unpublished)

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Abstract

The potential antimicrobial activity and acetylcholinesterase enzyme inhibition assay of water and methanol P. feotida extracts from fruits, leaves and stems were evaluated. Extracts from methanol fruits of P. feotida extract has found to be able to inhibit and resist the growth of pathogenic bacterial strains either Gram positive bacteria (Bacillus subtilis and Enterococcus faecalis) or Gram negative bacteria (Escherichia Coli and Pseudomonas aerogenosa). The identification of chemical constituents in P. feotida was done by UPLC-QTOF/MS and the results showed that this plant extract possessed a great number flavonoid compounds. With the presence of these compounds, it has contributed to the antimicrobial activity of P. feotida. Results of the present biological activity investigation further points to the potential of this plant species as a good source of new AChE inhibitors.

Item Type: Research Book Profile
Subjects: Q Science > Q Science (General)
T Technology > T Technology (General)
Faculty/Division: Faculty of Industrial Sciences And Technology
Depositing User: En. Mohd Ariffin Abdul Aziz
Date Deposited: 04 Jan 2023 02:02
Last Modified: 04 Jan 2023 02:02
URI: http://umpir.ump.edu.my/id/eprint/36245
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