M. M., Yusoff and Tan, Wei Hsiang (2012) Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract. International Journal of Pharma & Bio Sciences, 3 (4). pp. 629-637. ISSN 0975-6299. (Published)
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Abstract
A novel flavonoidic compound, 3,5-dihydroxy-4’,7-dimethoxyflavone, has been isolated from the rhizomes of Zingiber phillipseae. The dichloromethane extract of this species was shown to be non-toxic with LC50 for acute and toxic levels at 9,732 ppm and 562ppm, respectively. The extract showed higher antioxidant activity than the standard (butylated hydroxytoluene, BHT) but lower than dichloromethane extract of Zingiber officinale. It showed significant activity against Staphylococcus aureus and Escherichia coli with minimum inhibitory concentration (MIC) at 200µg/ml and 225 µg/ml respectively. Both extracts were found negative toward Candida albicans.
| Item Type: | Article |
|---|---|
| Additional Information: | IF: 0.67 Indexed in Elsevier |
| Uncontrolled Keywords: | Zingiber phillipseae; 3,5-dihydroxy-4’,7-dimethoxyflavone; Brine shrimp test; Antioxidant activity; Antimicrobial activity |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Faculty/Division: | Faculty of Industrial Sciences And Technology |
| Depositing User: | Prof. Dr. Mashitah Mohd Yusoff |
| Date Deposited: | 17 Mar 2014 07:53 |
| Last Modified: | 27 Jul 2018 03:26 |
| URI: | http://umpir.ump.edu.my/id/eprint/4732 |
| Download Statistic: | View Download Statistics |
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