Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract

M. M., Yusoff and Tan, Wei Hsiang (2012) Chemical And Biological Studies Of Zingiber Phillipseae Rhizomes Extract. International Journal of Pharma & Bio Sciences, 3 (4). pp. 629-637. ISSN 0975-6299. (Published)

[img] PDF (fist-2012-mashitah-ChemicalAndBiological)
fist-2012-mashitah-ChemicalAndBiological.pdf - Published Version
Restricted to Repository staff only

Download (227kB) | Request a copy


A novel flavonoidic compound, 3,5-dihydroxy-4’,7-dimethoxyflavone, has been isolated from the rhizomes of Zingiber phillipseae. The dichloromethane extract of this species was shown to be non-toxic with LC50 for acute and toxic levels at 9,732 ppm and 562ppm, respectively. The extract showed higher antioxidant activity than the standard (butylated hydroxytoluene, BHT) but lower than dichloromethane extract of Zingiber officinale. It showed significant activity against Staphylococcus aureus and Escherichia coli with minimum inhibitory concentration (MIC) at 200µg/ml and 225 µg/ml respectively. Both extracts were found negative toward Candida albicans.

Item Type: Article
Additional Information: IF: 0.67 Indexed in Elsevier
Uncontrolled Keywords: Zingiber phillipseae; 3,5-dihydroxy-4’,7-dimethoxyflavone; Brine shrimp test; Antioxidant activity; Antimicrobial activity
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Faculty/Division: Faculty of Industrial Sciences And Technology
Depositing User: Prof. Dr. Mashitah Mohd Yusoff
Date Deposited: 17 Mar 2014 07:53
Last Modified: 27 Jul 2018 03:26
Download Statistic: View Download Statistics

Actions (login required)

View Item View Item