Highly Active Thiol-functionalized SBA-15 Supported Palladium catalyst for Sonogashira and Suzuki-Miyaura Cross-coupling Reactions

Highly ordered mesoporous silica SBA-15 with pendent 3-mercaptopropyl groups has been prepared by
condensation of surface silanols and (3-mercaptopropyl)trimethoxysilane. Treatment of the
mercaptopropylated SBA-15 with (CH3CN)2PdCl2 gave a heterogeneous Pd-catalyst. The immobilized
Pd-catalyst served as an efficient heterogeneous catalyst for Sonogashira and Suzuki–Miyaura cross
coupling reactions of aryl halides. Furthermore, the SBA-15 supported Pd-catalyst was recovered by a
simple filtration from the reaction mixture and reused five times without significant loss of its catalytic
activity.