Nurul Akmal, Che Lah and Samykano, Mahendran and Trigueros, Sonia (2016) Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System. Journal of Nanomedicine Research, 4 (2). pp. 1-6. ISSN 2377-4282. (Published)
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Abstract
In the recent years, noble metal particles such as gold (Au) and silver (Ag) have been used progressively as efficient and safe nanoscale drug carriers in treating malignant as cites of cancerous cells. These single crystal structures of functionalised thearapeutic particles with the size less than 100 nm in diameter had proven offered an excellent function to modulate the oxidative stress and toxicity at affected membrane cells particularly to achieve the site-specific delivery of drugs. This mini-review will highlight the current advances of Au and Ag nanoscale particles as smart chemotherapeutic molecule carriers to these malignancies in impeding cancer cell activities locally. The paper also reviewed valuable insights of their efficacy in maintaining and precisely control the drugs release level within the therapeutic windows.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Nanoscale Metal Particles; Nanocarriers; Drug Delivery System |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology |
| Faculty/Division: | Faculty of Mechanical Engineering |
| Depositing User: | Noorul Farina Arifin |
| Date Deposited: | 08 Mar 2017 01:03 |
| Last Modified: | 08 Mar 2017 01:03 |
| URI: | http://umpir.ump.edu.my/id/eprint/16455 |
| Download Statistic: | View Download Statistics |
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