Evaluation of Antilipolytic, Antioxidant and Antibacterial Activities of Selected Ferns

Jarial, Rini and Singh, Lakhveer and Thakur, Sveta and Zularisam, A. W. and Mimi Sakinah, A. M. and S. S., Kanwar (2017) Evaluation of Antilipolytic, Antioxidant and Antibacterial Activities of Selected Ferns. Journal of Applied Pharmaceutical Science, 7 (6). pp. 150-156. ISSN 2231-3354. (Published)

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In the present study, three ferns were used (Adiantum capillus-veneris Cheilanthes albomarginata and Asplenium pumilum,) to identify their functional compounds to reduce obesity. The methanolic fern-extract (MFE) of these ferns was assessed for anti-bacterial activity by measuring inhibition zones against a panel of pathogenic bacterial strains using the agar diffusion method. MFE at a concentration of 25 μg /ml showed marked anti-bacterial activity against all bacterial strains (6mm to 23mm) zone of inhibition and was greatest against Enterobacter sp (23 mm). Out of these, the MFE of the A. veneris fern extract had the best MIC values of 2.25 μg /ml against S. aureus and Enterobacter sp. respectively. It had an inhibitory concentration (69.9 %) for 2, 2-diphenylpicryl-1-picryl-hydrazyl (DPPH) scavenging activity. The MFE of the A. veriens also possessed good anti-lipolytic activity (76.5%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (89%). The hemolytic activity of A. veneris was found to be 27.6% at 6.25 µg/mL of MFE. This result showed that the MFE of A. veriens is not only a potent source of natural anti-oxidants and anti-bacterial activities but also possesses efficient cholesterol degradation and anti-lipolytic activities, which would be beneficial in body weight management.

Item Type: Article
Uncontrolled Keywords: Adiantum capillus-veneris; Cheilanthes albomarginata; Asplenium pumilum; Antioxidant; Anti-lipolytic; Antihemolytic
Subjects: T Technology > T Technology (General)
Faculty/Division: Faculty of Engineering Technology
Institute of Postgraduate Studies
Depositing User: Mrs. Neng Sury Sulaiman
Date Deposited: 08 Sep 2017 02:31
Last Modified: 03 Oct 2019 07:51
URI: http://umpir.ump.edu.my/id/eprint/18391
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