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A clinical update on antibiotic resistance gram-negative bacteria in Malaysia- a review

M. K. K., Fazlul and Rashid, Shah Samiur and M. H. M., Nazmul and I. S. M., Zaidul and R., Baharudin and A. N. M., Ramli (2018) A clinical update on antibiotic resistance gram-negative bacteria in Malaysia- a review. Journal of International Pharmaceutical Research, 45. pp. 270-283. ISSN 1674-0440

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Abstract

Antibiotics are the wonder discoveries to combat microbes. For decades, multiple varieties of antibiotics have been used for therapeutic purposes in hospital settings and communities throughout the world. Unfortunately, bacteria have become resistant to commonly prescribed antibiotics. This review aims to explore the development, challenges, and the current state of antibiotic resistance available literature in Malaysia. Recently published data from Pubmed, Scopus, Google scholar’s and other internet source publication on the antibiotic resistance of gram-negative bacteria were further reviewed and analysed in this study. This review reiterates the antibiotic resistance among the gram-negative bacteria is increasing and they are becoming resistant to nearly all groups of antibiotics. The antibiotic treatments are minimal and hard to treat in multi-drug resistance bacterial infection, resulting in morbidity and mortality. The prevalence rate of antibiotic resistance from the literature suggests that educating patients and the public is essential to prevent and control the spread of antibiotic resistance. In particular, there is an urgent need for a surveillance system of regular monitoring on the microbiomes, the discovery of novel antibiotics and therapeutic application of antibiotics are mandatory.

Item Type: Article
Uncontrolled Keywords: Acinetobacter; Antimicrobial resistance; Pseudomonas
Subjects: Q Science > Q Science (General)
Faculty/Division: Faculty of Industrial Sciences And Technology
Depositing User: Noorul Farina Arifin
Date Deposited: 26 Nov 2018 08:40
Last Modified: 11 Feb 2019 00:29
URI: http://umpir.ump.edu.my/id/eprint/22938
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