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Correlation between the extraction yield of mangiferin to the antioxidant activity, total phenolic and total flavonoid content of Phaleria macrocarpa fruits

Lim, Yee Peng and Pang, Sook Fun and M. M., Yusoff and Siti Kholijah, Abdul Mudalip and Jolius, Gimbun (2019) Correlation between the extraction yield of mangiferin to the antioxidant activity, total phenolic and total flavonoid content of Phaleria macrocarpa fruits. Journal of Applied Research on Medicinal and Aromatic Plants, 14 (100224). pp. 1-11. ISSN 2214-7861

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Abstract

This paper elucidates the correlation between the yield of mangiferin extraction from Phaleria macrocarpa fruits to the total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity (AA). Mangiferin extraction was performed using an ultrasonic assisted extraction (UAE) method. The effect of particle size, solvent to solid ratio, solvent type, ethanol concentration, sonication amplitude and extraction time were studied. The best UAE condition was found using a particle size of 125–250 μm, solvent to solid ratio of 40 mL/g, 40% ethanol, sonication amplitude of 60% and extraction time of 5 min, which produced 28.6 mg mangiferin/g DW, 78.7 mg GA/g DW, 263.2 mg QE/g DW and 57.2% DPPH-RSA. The regression analysis showed a significant (p < 0.05) correlation between the mangiferin yield and either TPC, TFC or AA. The finding reported in this work provides a useful method to predict the mangiferin yield based on TPC, TFC or AA, without needing the actual external standard.

Item Type: Article
Uncontrolled Keywords: Ultrasonic assisted extraction, Mangiferin, Antioxidant activity, UHPLC-PDA
Subjects: T Technology > TP Chemical technology
Faculty/Division: Centre of Excellence: Centre of Excellence for Advanced Research in Fluid Flow
Faculty of Chemical & Natural Resources Engineering
Faculty of Industrial Sciences And Technology
Depositing User: P. M. Dr. Jolius Gimbun
Date Deposited: 08 Oct 2019 08:52
Last Modified: 08 Oct 2019 08:52
URI: http://umpir.ump.edu.my/id/eprint/26020
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