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Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization

Abbas, Shabudin and Mohd Jamil Mohamed, Mokhtarudin and Payne, Stephen J. and Nik Abdullah, Nik Mohamed (2019) Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization. In: 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE 2019), 10-12 June 2019 , Japan. pp. 1-4..

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Abstract

Existing brain model to study brain oedema formation has an assumption of homogeneous brain capillary distribution, despite it is actually normally distributed. In this paper, the assumption is improved by applying asymptotic expansion homogenization (AEH) to a vascularized poroelastic model to obtain a new homogenized macroscale governing equations with 4 microscale cell problems. The cell problems are solved on a cube of brain tissue with capillary to obtain 4 tensors describing the mechanical and fluid transport properties of the brain. From the simulations, only the blood permeability and Biot’s parameter tensors are significantly affected by the capillary tortuosities.

Item Type: Conference or Workshop Item (Lecture)
Uncontrolled Keywords: Asymptotic Expansion Homogenization; Poroelastic Theory; Brain Tissue; Ischaemic Stroke; Cell Problems
Subjects: T Technology > TJ Mechanical engineering and machinery
Faculty/Division: Faculty of Mechanical Engineering
Depositing User: Pn. Hazlinda Abd Rahman
Date Deposited: 17 Dec 2019 04:27
Last Modified: 17 Dec 2019 04:27
URI: http://umpir.ump.edu.my/id/eprint/26044
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