Nasrul Hadi, Johari and Menichini, Claudia and Hamady, Mohamad and Xu, Xiao Y. (2019) Effects of stent design on LDL accumulation at the carotid artery bifurcation. In: 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE 2019) , 10-12 June 2019 , Japan. pp. 1-4.. (Unpublished)
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Abstract
Restenosis typically occurs in regions of low and oscillating wall shear stress which also favours the accumulation of atherogenic macromolecules such as low-density lipoprotein (LDL). This study aims to determine how stent strut design may affect in-stent restenosis at the carotid artery bifurcation following carotid artery stenting (CAS) by means of computational simulation. LDL concentrations were compared for post-stent carotid and the contralateral models reconstructed from patient-specific images. Our results show that closed-cell stent designs are more likely to create atheroprone and procoagulant flow conditions than open-cell designs due to larger area exposed to high LDL concentration.
Item Type: | Conference or Workshop Item (Lecture) |
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Uncontrolled Keywords: | Stent Design; Carotid Artery Stenting; Low-Density Lipoprotein |
Subjects: | T Technology > TJ Mechanical engineering and machinery |
Faculty/Division: | Faculty of Mechanical Engineering |
Depositing User: | Pn. Hazlinda Abd Rahman |
Date Deposited: | 23 Dec 2019 07:19 |
Last Modified: | 23 Dec 2019 07:19 |
URI: | http://umpir.ump.edu.my/id/eprint/26483 |
Download Statistic: | View Download Statistics |
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