Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms

Jarial, Rini and Singh, Lakhveer and Zularisam, A. W. and Kanwar, S. S. (2017) Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms. IIUM Engineering Journal, 18 (2). pp. 56-62. ISSN 1511-788X. (Published)

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The aim of the present study was to evaluate the therapeutic properties of selected fern, Chelianthusalbomarginata and to identify its functional compounds. The methanolic fern-extract (MFE) of these ferns was assessed for anti-bacterial activities by measuring inhibition zones against a panel of pathogenic bacterial strains using agar diffusion method. MFE at a concentration of 25 μg/ml showed marked anti-bacterial activity against all bacterial strains (6-23mm zone of inhibition) and was maximum against Enterobacter sp (23 mm). In addition, the MFE of C. albomarginata had the best MIC values of 2.25µg/ml against S. aureus and Enterobacter sp., respectively. The MFE also possessed good anti-lipolytic activity (66.5%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (79%). This result showed that MFE of C. albomarginata under optimal concentration is not only a potent source of natural anti-oxidants and anti-bacterial activity but also possesses efficient cholesterol degradation and anti-lipolytic activities, that is to be beneficial in the body weight management.

Item Type: Article
Additional Information: Indexed by Scopus
Uncontrolled Keywords: Chelianthesalbomarginata; Phytochemicals; Anti-oxidant; Antibacterial; Antilipolytic
Subjects: T Technology > TP Chemical technology
Faculty/Division: Faculty of Engineering Technology
Institute of Postgraduate Studies
Depositing User: Mrs Norsaini Abdul Samat
Date Deposited: 10 Nov 2022 01:48
Last Modified: 10 Nov 2022 01:48
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