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A review on lipid-polymer hybrid nanoparticles and preparation with recent update

Subashini, Raman and Mahmood, Syed and Rahman, Azizur (2020) A review on lipid-polymer hybrid nanoparticles and preparation with recent update. Materials Science Forum, 981. pp. 322-327. ISSN 0255-5476

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Abstract

Ongoing progression in nanotechnology has demonstrated that nanoparticles have indicated promising potential as in delivering the drug. The acceptance of nanoparticles and their applications also reported in clinical advancement to upgrade and improve the pharmacokinetic and pharmacodynamics properties of therapeutic compounds. In this review, we talk about the next-generation core-shell nanostructures like lipid-polymer hybrid nanoparticles (LHNPs) and their application and formulation aspects. Conceptually, derived from both polymeric nanoparticles and liposome, which gave them a name of hybrid nanoparticles. It is basically polymer core enveloped by a lipid layer. The major issue arises with nanoparticles with polymer is related to entrapment efficiency and LHNPs have proved to solve this issue to a vast extent, due to their hybrid components.

Item Type: Article
Additional Information: Indexed by Scopus
Uncontrolled Keywords: Emulsion Method; Lipid-Polymer Hybrid Nanoparticles (LPHNs); Nanoparticles
Subjects: T Technology > T Technology (General)
Faculty/Division: Faculty of Engineering Technology
Institute of Postgraduate Studies
Depositing User: Pn. Hazlinda Abd Rahman
Date Deposited: 11 Jan 2021 08:13
Last Modified: 05 Feb 2021 03:26
URI: http://umpir.ump.edu.my/id/eprint/30374
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