Hepatitis C virus (HCV) diagnosis via microfluidics

Narayanamurthy, Vigneswaran and Jeroish, Z E. and Bhuvaneshwari, K. S. and Fahmi, Samsuri (2021) Hepatitis C virus (HCV) diagnosis via microfluidics. Analytical Methods, 13 (6). pp. 740-763. ISSN 1759-9660 (print); 1759-9679 (online). (Published)

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Humans are subjected to various diseases; hence, proper diagnosis helps avoid further disease consequences. One such severe issue that could cause significant damage to the human liver is the hepatitis C virus (HCV). Several techniques are available to detect HCV under various categories, such as detection through antibodies, antigens, and RNA. Although immunoassays play a significant role in discovering hepatitis viruses, there is a need for point-of-care tests (POCT). Some developing strategies are required to ensure the appropriate selection of POCT for HCV detection, initiate appropriate antiviral therapy, and define associated risks, which will be critical in achieving optimal outcomes. Though molecular assays are precise, reproducible, sensitive, and specific, alternative strategies are required to enhance HCV diagnosis among the infected population. Herein, we described and assessed the potential of various microfluidic detection techniques and confirmatory approaches used in present communities. In addition, current key market players in HCV chip-based diagnosis and the future perspectives on the basis of which the diagnosis can be made easier are presented in the present review

Item Type: Article
Uncontrolled Keywords: Hepatitis C virus; HCV; HCV diagnosis via microfluidics
Subjects: T Technology > TA Engineering (General). Civil engineering (General)
T Technology > TP Chemical technology
Faculty/Division: Institute of Postgraduate Studies
College of Engineering
Depositing User: Miss. Ratna Wilis Haryati Mustapa
Date Deposited: 01 Sep 2021 07:22
Last Modified: 01 Sep 2021 07:22
URI: http://umpir.ump.edu.my/id/eprint/31919
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