Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients

Najwa Hidayah, Abdul Razak Ramesh and Mohd Riduwan, Ghazali and Mohd Ashraf, Ahmad (2021) Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients. Bulletin of Electrical Engineering and Informatics, 10 (2). 632 -639. ISSN 2089-3191 (Print); 2302-9285 (Online). (Published)

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Abstract

This paper emphasizes on the development of an appropriate closed-loop control strategy for traditional portable duodopa pump (PDP); thereby ensuring an automated drug infusion without wearing off. In particular, a sigmoid proportional integral derivative (SPID) controller is adopted to control the blood plasma level of dopamine. The parameters of SPID controller are tuned using the adaptive safe experimentation dynamics (ASED) algorithm. The efficiency of the suggested SPID-ASED is evaluated by concerning the convergence plot of the cost function, the amount of dopamine in the blood plasma (BP) of the patient, the statistical analysis of cost function, norm of error and norm of input, and time responses specifications. The simulation results show that the proposed SPID-ASED outperforms the standard PID controller in terms of better control accuracy with minimum overshoot and settling time.

Item Type: Article
Additional Information: Indexed by Scopus
Uncontrolled Keywords: ASED; Dopamine; Duodopa pump; Parkinson’s disease; SPID controller
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering
Faculty/Division: Institute of Postgraduate Studies
Faculty of Electrical and Electronic Engineering Technology
Depositing User: Mrs Norsaini Abdul Samat
Date Deposited: 10 Jan 2022 00:55
Last Modified: 10 Jan 2022 00:55
URI: http://umpir.ump.edu.my/id/eprint/32264
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