Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds

Nor Naimah, Hussin @ Hassan and Noor Suhana, Adzahar and Lee, Thong Chuan and Izan Izwan, Misnon and Venugopal, Jayarama Reddy (2023) Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds. Malaysian Applied Biology, 52 (4). pp. 107-112. ISSN 0126-8643. (Published)

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Abstract

Natural products and essential oils of medicinal plants are extensively employed in wound healing, particularly in the pharmaceutical industry. Essential oils obtained from Psidium guajava were utilised as an antibacterial agent against Bacillus subtilis, Staphylococcus aureus, and Enterococcus faecalis, and to control drug-resistant strains. In this study, electrospinning for applications in antimicrobial activity and drug delivery systems was used to develop biocomposite nanofibers of Polycaprolactone (PCL)/Cellulose Acetate (CA) and Psidium guajava essential oil (PGEO). Images from the FESEM revealed that the mean fire diameters were 120 nm for the PCL/CA and 223 nm for PCL/CA/PGEO biocomposite nanofibers. The diameters of the nanofibers were increased following the addition of PGEO into PCL/CA nanofibers. Furthermore, FTIR studies revealed the-OH peak in pure electrospun PCL/CA and PCL/CA/PGEO, lacking pure PGEO nanofibrous mats. These findings reflect that Psidium guajava essential oil/PCL/CA electrospun nanofibers are promising candidates for presenting bioactive compounds in wound management or other approaches for wound healing and bacterial infections.

Item Type: Article
Additional Information: Indexed by Scopus
Uncontrolled Keywords: Biocomposite nanofibers; Cellulose acetate (CA); Polycaprolactone (PCL); Psidium guajava essential oil (PGEO); Wound healing
Subjects: H Social Sciences > HD Industries. Land use. Labor
Q Science > Q Science (General)
T Technology > T Technology (General)
Faculty/Division: Faculty of Industrial Sciences And Technology
Institute of Postgraduate Studies
Depositing User: Mr Muhamad Firdaus Janih@Jaini
Date Deposited: 07 Jan 2025 04:58
Last Modified: 07 Jan 2025 04:58
URI: http://umpir.ump.edu.my/id/eprint/42863
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