Cross-Linking Effect on Electrospun Hydroxyethyl Cellulose/Poly(Vinyl Alcohol) Nanofibrous Scaffolds

Farah Hanani, Zulkifli and Jahir Hussain, Fathima Shahitha and M. M., Yusoff and Nurul Nadiah, Hamidon and Sugandha, Chahal (2013) Cross-Linking Effect on Electrospun Hydroxyethyl Cellulose/Poly(Vinyl Alcohol) Nanofibrous Scaffolds. Procedia Engineering, 53. pp. 689-695. ISSN 1877-7058. (Published)

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DOI/Official URL: http://dx.doi.org/10.1016/j.proeng.2013.02.089

Abstract

The electrospinning of hydroxyethyl cellulose/poly(vinyl alcohol) (HEC/PVA) was carried out with glutaraldehyde as a cross li nker to fabricate water insoluble nanofibers. The concentration of HEC (5wt%) and PVA (15wt%) was prepared and blended in different weight ratios of HEC to PVA (50:50, 40:60 and 70:30) were electrospun to get nanofibers. The microstructure of the obtained nanofibers were analysed by scanning electron microscopy (SEM) and X-ray diffraction (XRD) before and after crosslinking. SEM images showed that there was no swelling or remarkable changes in the surface morphology after treated with glutaraldehyde. XRD analysis il lustrated the effect of crosslinking on the crystallinity of the nanofibers. The results showed that these crosslinked HEC/PVA fibers were suitable for variety of applications such as tissue engineering scaffolds, drug delivery and medical prostheses.

Item Type:	Article
Uncontrolled Keywords:	Modified cellulose; Poly (vinyl alcohol); Electrospinning; Nanofibers scaffolds; Bone tissue engineering
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Faculty/Division:	Faculty of Industrial Sciences And Technology
Depositing User:	Prof. Dr. Mashitah Mohd Yusoff
Date Deposited:	28 Jan 2014 07:52
Last Modified:	26 Jul 2018 06:56
URI:	http://umpir.ump.edu.my/id/eprint/4792
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