Sarkar, Shaheen M. and Md. Eaqub, Ali and Lutfor, M. R. and M. M., Yusoff Preparation of Mesoporous Silica-Supported Chiral Amino Alcohols for the Enantioselective Addition of Diethylzinc to Aldehyde and Asymmetric Transfer Hydrogenation to Ketones. Journal of Nanomaterials (Articl). pp. 1-6. ISSN 1687-4110 (print); 1687-4129 (online). (Published)
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Abstract
Optically active (−)-ephedrine, (−)-norephedrine, and (−)-prolinol were immobilized onto cubicmesoporousMCM-48 silica. The immobilized amino alcohols served as a heterogeneous chiral catalyst for the asymmetric addition of diethylzinc to aldehydes and transfer hydrogenation to ketones. The developed catalytic process yielded optically enriches secondary aromatic alcohols with 92–99% conversion and 70–82% enantioselectivity.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Faculty/Division: | Faculty of Industrial Sciences And Technology |
| Depositing User: | Dr. Md Shaheen Sarkar |
| Date Deposited: | 12 Jan 2015 02:03 |
| Last Modified: | 14 Feb 2018 04:12 |
| URI: | http://umpir.ump.edu.my/id/eprint/8176 |
| Download Statistic: | View Download Statistics |
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