Vijayalakshmi, A. and Jayakumari, S. and Masilamani, K. (2016) In-vitro Antioxidant Potential of the Flavonoid Glycosides from Cassia tora linn. Leaves. International Journal of Engineering Technology And Sciences (IJETS), 5 (1). pp. 19-26. ISSN 2289-697X. (Published)
PDF
In-vitro antioxidant potential of the flavonoid glycosides from Cassia tora linn. Leaves.pdf Restricted to Repository staff only Download (552kB) | Request a copy |
||
|
PDF
ftech-2016-masilamani-Invitro antioxidant potential1.pdf Download (41kB) | Preview |
Abstract
The present study aimed to study the anti-oxidant potential of isolated flavonoids from the ethanol extract (70%v/v) of Cassia tora leaves. Three flavonoids were isolated viz Luteolin-7-O-β-glucopyranoside (I), quercetin-3-O-β-d-glucuronide (II) and Formononetin-7-O-β-D-Glucoside (III) from the ethanol extract (70%v/v) of Cassia tora leaves in the previous study. A comprehensive study on the phytochemical contents - total phenolic content and flavonoid content was accessed using Folin-Denis and AlCl3 method respectively. The antioxidant potential of the samples was evaluated using inhibition of hydroxyl radical, 2,2-diphenyl-1- picrylhydrazyl (DPPH), and nitric oxide scavenging methods. The total phenolic content and flavonoid content was found to be 18.60 % w/w and 9.5% w/w respectively. The IC50 values of ethanol extract against hydroxyl, DPPH and nitric oxide radical were found to be 270 µg/mL, 190 µg/mL and 130 µg/mL respectively. The radical scavenging activity of the isolated flavonoids decreased in the following order: quercetin (IC50 values 15, 14, 18 µg/mL) >formononetin (IC50 values 19, 21, 14 µg/mL) > luteolin (IC50 values 20, 23, 18 µg/mL) respectively. Index terms - Cassia tora, flavonoids, HPTLC, antioxidant
Item Type: | Article |
---|---|
Uncontrolled Keywords: | Cassia tora, flavonoids, HPTLC, antioxidant |
Subjects: | T Technology > T Technology (General) |
Faculty/Division: | Faculty of Engineering Technology |
Depositing User: | Mrs. Neng Sury Sulaiman |
Date Deposited: | 18 Aug 2016 06:50 |
Last Modified: | 01 Feb 2018 06:47 |
URI: | http://umpir.ump.edu.my/id/eprint/13806 |
Download Statistic: | View Download Statistics |
Actions (login required)
View Item |