Alara, Oluwaseun Ruth and Nour, A. H. and Siti Kholijah, Abdul Mudalip and Olalere, Olusegun Abayomi (2018) Two-level factorial design for the extraction of phenolics and flavonoids from chromolaena odorata leaves. In: 4th International Conference Of Chemical Engineering And Industrial Biotechnology (ICCEIB 2018) , 1-2 Aug 2018 , Seri Pacific Hotel, Kuala Lumpur. pp. 520-521.. (Unpublished)
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Abstract
Chromolaena odorata (Bitter bush) belongs to the family Asteraceae. It is used as a source of medicine especially in Asia and West Africa countries [1]. Phenolic compounds are mostly distributed group of phytochemicals that possess a wide range of physiological activities like antiinflammatory, anti-cancer, vasodilatory effects, antioxidant, and among others [2]. Several phenolic compounds have been extracted and isolated from this plant, including vanillic acid, pcoumaric, protocatechuic, quercetin, luteolin, kaempferol, and among others [3]. The effects of microwave-assisted extraction (MAE) variables on the recovery yields of total phenolic content (TPC) and total flavonoid content (TFC) from Chromolaena odorata leaves were investigated using single factor experiment and two-level factorial design. The examined MAE variables were irradiation time, A (1-5 min), microwave power level, B (400-800 W), temperature, C (60-80 °C), solvent-feed ratio, D (8-14 ml/g) and ethanol concentration, E (20-60%). The obtained results showed that irradiation time (3.90 %), microwave power level (14.93 %) and ethanol concentration (17.21 %) significantly contributed to the recoveries of TPC and TFC from Chromolaena odorata leaves (Fig. 1). This implies that irradiation time, microwave power and ethanol concentration were significant (p < 0.05) in obtaining higher recoveries. Thus, the significant variables will be considered for the optimization process
| Item Type: | Conference or Workshop Item (Speech) |
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| Uncontrolled Keywords: | Extraction; Phenolics; Flavonoids |
| Subjects: | T Technology > TP Chemical technology |
| Faculty/Division: | Faculty of Chemical & Natural Resources Engineering Institute of Postgraduate Studies |
| Depositing User: | Prof. Dr. Abdurahman Nour |
| Date Deposited: | 20 Sep 2018 06:34 |
| Last Modified: | 10 Sep 2019 06:50 |
| URI: | http://umpir.ump.edu.my/id/eprint/21931 |
| Download Statistic: | View Download Statistics |
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