Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process

Ummi Najihah, Md Hashim (2016) Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process. Faculty of Chemical & Natural Resources Engineering, Universiti Malaysia Pahang.

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Abstract

Mahkota Dewa or scientifically known as Phaleria Macrocarpa is a popular herbal plant in Indonesia and Malaysia. The bioactive ingredient in this plant process antihistamine, antioxidant, anti-cancer compound. In this work, experimental studies were performed using subcritical water extraction process to extract the bioactive compound namely mangiferin from Mahkota Dewa fruits. The effect of process parameters which are solid to solvent ratios (30, 40, 50, 60, and 70 g/L), temperature (50, 75, 100, 125, 150 °C) and extraction time (3, 4, 5, 6, 7 h) on the extraction yields were investigated. The extraction yields were analysed and characterised using high performance liquid chromatography (HPLC) and 1,1-Diphenyl-2-picryl hydrazyl (DPPH) assay method, respectively. The highest mangiferin yield is 3.2027w/w % were obtained at 60 g/L of solid to solvent ratio, 100 °C of extraction temperature and 5 h of extraction time. The highest of antioxidant activity is 86.5377 % were obtained at 60 g/L of solid to solvent ratio, 125 °C of extraction temperature, 5 h of extraction time. Antioxidant is defined as a substance which significantly delays or inhibits oxidant process. The high value of antioxidant was obtained from the highest value of DPPH since the remaining DPPH in sample acts free radicals were increased in reactivity of unpaired electron and allowed the development of tissues damage in living organisms.

Item Type: Undergraduates Project Papers
Additional Information: Project Paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2017, SV: DR. SITI KHOLIJAH BINTI ABDUL MUDALIP, NO. CD: 11176
Uncontrolled Keywords: Mahkota Dewa; subcritical water extraction
Subjects: T Technology > TP Chemical technology
Faculty/Division: Faculty of Chemical & Natural Resources Engineering
Depositing User: Mrs. Sufarini Mohd Sudin
Date Deposited: 13 Dec 2018 02:13
Last Modified: 16 Nov 2023 07:14
URI: http://umpir.ump.edu.my/id/eprint/22628
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