Hazrulrizawati, Hamid and Roziasyahira, Mutazah (2019) Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity. Iranian Journal of Science and Technology, Transaction A: Science, 43 (5). pp. 2219-2225. ISSN 1028-6276. (Published)
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Abstract
The present study reported a simple method in synthesizing silver nanoparticles (AgNPs) by using Clinacanthus nutans extract. The UV–visible spectra showed the characteristic absorption peak at 480 nm, and the intensity was increased with the increase in plant extract ratio and incubation period. Analysis of particle size through FESEM, XRD and TEM revealed the average of synthesized AgNPs is 73.4 nm. The EDX analysis confirmed the formation of metallic nature of silver. The FTIR spectra indicated the role of carbonyl groups in the synthetic process and further confirmed by identification of flavonoids and their glycosides by UPLC-QTOF/MS. Antimicrobial activity of biosynthesized AgNPs shows effective inhibition against common bacterial strains including Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Proteus vulgaris.
| Item Type: | Article |
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| Additional Information: | Indexed by Scopus |
| Uncontrolled Keywords: | Silver nanoparticles; Clinacanthus nutans; Antimicrobial activity; UPLC-QTOF/MS; Flavonoids |
| Subjects: | T Technology > TP Chemical technology |
| Faculty/Division: | Faculty of Industrial Sciences And Technology Institute of Postgraduate Studies |
| Depositing User: | Mrs Norsaini Abdul Samat |
| Date Deposited: | 12 Mar 2020 07:01 |
| Last Modified: | 12 Mar 2020 07:01 |
| URI: | http://umpir.ump.edu.my/id/eprint/26793 |
| Download Statistic: | View Download Statistics |
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