Vigneswaran, Narayanamurthy and Nagarajan, Sairam and Al'aina Yuhainis, Firus Khan and Fahmi, Samsuri and Sridhar, T. M. (2017) Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications. Analytical Methods, 9 (25). pp. 3751-3772. ISSN 1759-9660 (print); 1759-9679 (online). (Published)
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Abstract
The development of hydrodynamic-based microfluidic biochips has been increasing over the years. In this technique, the cells or particles are trapped in a particular region for single cell analysis (SCA) usually without any application of external force fields such as optical, electrical, magnetic or acoustic. There is a need to explore the insights of SCA in the cell's natural state and development of these techniques is highly essential for that study. Researchers have highlighted the vast potential field that needs to be explored to develop biochip devices to suit market/researcher demands. Hydrodynamic microfluidics facilitates the development of passive lab-on-chip applications. This review gives an account of the recent advances in this field, along with their mechanisms, methods and applications.
| Item Type: | Article |
|---|---|
| Additional Information: | Indexed by Scopus |
| Uncontrolled Keywords: | External force field; Hydrodynamic trapping; Lab on chip; Micro fluidic biochips; Potential field; Singlecell analysis |
| Subjects: | Q Science > QC Physics T Technology > T Technology (General) T Technology > TK Electrical engineering. Electronics Nuclear engineering |
| Faculty/Division: | Faculty of Electrical & Electronic Engineering Institute of Postgraduate Studies |
| Depositing User: | Mrs Norsaini Abdul Samat |
| Date Deposited: | 07 Nov 2022 07:37 |
| Last Modified: | 07 Nov 2022 07:37 |
| URI: | http://umpir.ump.edu.my/id/eprint/29118 |
| Download Statistic: | View Download Statistics |
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