Yeong, Yi Ling and Pang, Sook Fun and Putranto, Aditya and Jolius, Gimbun (2021) Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb. Natural Product Research. pp. 1-5. ISSN 1478-6427. (In Press / Online First) (In Press / Online First)
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Abstract
AbstractThis paper investigates the optimum processing conditions of microwave assisted extraction (MAE) of anthraquinone (aloe emodin, AE) and flavonoids (kaempferol 3-gentiobioside, K3G and kaempferol, KA) from Senna alata (L.) Roxb. The kinetic study indicates that MAE showed a greater extraction rate, compared to ultrasonic-assisted and maceration, due to the enhanced power which altered the leaf microstructures. The optimisation was undertaken using one-factor-at-a-time, two-level factorial design and central composite design were used to maximise the yield of the target compounds. The optimum yield of K3G (4.27 mg/g DW), KA (8.54 mg/g DW) and AE (0.86 mg/g DW) was obtained at 90.5% ethanol, microwave power of 18.6 W/mL with a desirability of 0.82. In addition, the yield of K3G and KA is correlated positively with the antioxidant activity.
| Item Type: | Article |
|---|---|
| Additional Information: | PMID: 33538194 |
| Uncontrolled Keywords: | Microwave assisted extraction; Senna alata; antioxidant; kaempferol 3-gentiobioside; kaempferol; aloe emodin |
| Subjects: | T Technology > TP Chemical technology |
| Faculty/Division: | Centre of Excellence: Centre of Excellence for Advanced Research in Fluid Flow Institute of Postgraduate Studies College of Engineering |
| Depositing User: | Prof. Dr. Jolius Gimbun |
| Date Deposited: | 17 Sep 2021 04:46 |
| Last Modified: | 17 Sep 2021 04:49 |
| URI: | http://umpir.ump.edu.my/id/eprint/31920 |
| Download Statistic: | View Download Statistics |
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