Firwana, Younis M.S. and Mohd Khairul Izamil, Zolkefley and Hasnetty Zuria, Mohamed Hatta and Rowbin, Christina and Che Nasril, Che Mohd Nassir and Muhammad Hafiz, Hanafi and Mohd Shafie, Abdullah and Keserci, Bilgin M. and Lannin, Natasha A. and Muzaimi, Mustapha Regional cerebral blood perfusion changes in chronic stroke survivors as potential brain correlates of the functional outcome following gamiied home-based rehabilitation (IntelliRehab)—a pilot study. Journal of NeuroEngineering and Rehabilitation, 19 (94). pp. 1-14. ISSN 1743-0003. (Published)
|
Pdf
Regional cerebral blood perfusion changes in chronic stroke survivors as potential brain correlates of the functional outcome.pdf Available under License Creative Commons Attribution. Download (1MB) | Preview |
Abstract
Background: Hospital-based stroke rehabilitation for stroke survivors in developing countries may be limited by staffing ratios and length of stay that could hamper recovery potential. Thus, a home-based, gamified rehabilitation system (i.e., IntelliRehab) was tested for its ability to increase cerebral blood flow (CBF), and the secondary impact of changes on the upper limb motor function and functional outcomes. Objective: To explore the effect of IntelliRehab on CBF in chronic stroke patients and its correlation with the upper limb motor function. Methods: Two-dimensional pulsed Arterial Spin Labelling (2D-pASL) was used to obtain CBF images of stable, chronic stroke subjects (n = 8) over 3-months intervention period. CBF alterations were mapped, and the detected differences were marked as regions of interest. Motor functions represented by Fugl-Meyer Upper Extremity Assessment (FMA) and Stroke Impact Scale (SIS) were used to assess the primary and secondary outcomes, respectively. Results: Regional CBF were significantly increased in right inferior temporal gyrus and left superior temporal white matter after 1-month (p = 0.044) and 3-months (p = 0.01) of rehabilitation, respectively. However, regional CBF in left middle fronto-orbital gyrus significantly declined after 1-month of rehabilitation (p = 0.012). Moreover, SIS-Q7 and FMA scores significantly increased after 1-month and 3-months of rehabilitation. There were no significant correlations, however, between CBF changes and upper limb motor function. Conclusions: Participants demonstrated improved motor functions, supporting the benefit of using IntelliRehab as a tool for home-based rehabilitation. However, within-participant improvements may have limited potential that suggests the need for a timely administration of IntelliRehab to get the maximum capacity of improvement.
| Item Type: | Article |
|---|---|
| Additional Information: | Indexed by Scopus |
| Uncontrolled Keywords: | Arterial spin labeling; Cerebral blood flow; Chronic stroke; Telerehabilitation; Upper extremity |
| Subjects: | H Social Sciences > HD Industries. Land use. Labor > HD28 Management. Industrial Management Q Science > Q Science (General) T Technology > T Technology (General) |
| Faculty/Division: | Faculty of Industrial Sciences And Technology Institute of Postgraduate Studies |
| Depositing User: | Mr Muhamad Firdaus Janih@Jaini |
| Date Deposited: | 16 Aug 2023 04:46 |
| Last Modified: | 16 Aug 2023 04:46 |
| URI: | http://umpir.ump.edu.my/id/eprint/37399 |
| Download Statistic: | View Download Statistics |
Actions (login required)
 |
View Item |