Advances in the pharmacotherapeutic applications of hyaluronic acid: A comprehensive review

Urbi, Zannat and Nina Suhaity, Azmi and Hossain, Md. Sanower (2023) Advances in the pharmacotherapeutic applications of hyaluronic acid: A comprehensive review. Materials Today: Proceedings. ISSN 2214-7853. (In Press / Online First) (In Press / Online First)

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Abstract

Natural non-sulfated glycosaminoglycan hyaluronic acid (HA), a biopolymer, has a variety of functions in controlling different biological processes. However, articular cartilage and synovial fluid contain more HA than other tissues and fluids. Over the past few decades, HA has been employed as a pharmacotherapeutic for a variety of conditions, such as osteoarthritis, cartilage regeneration, and wound healing. HA is used to create scaffold materials appropriate for tissue engineering because of its unique physicochemical characteristics. Recent cutting-edge research has shown that the molecular weight (Mw) of HA affects its efficacy. This paper provided a summary of recent developments in several pharmacotherapeutic applications and recommended research areas in order to improve HA activity.

Item Type: Article
Uncontrolled Keywords: Biomedical application; Biopolymer; Glycosaminoglycan; Tissue Engineering; Scaffolds
Subjects: H Social Sciences > HD Industries. Land use. Labor > HD28 Management. Industrial Management
T Technology > T Technology (General)
Faculty/Division: Faculty of Industrial Sciences And Technology
Institute of Postgraduate Studies
Centre for Sustainability of Mineral & Resource Recovery Technology (SMARRT)
Depositing User: Miss Amelia Binti Hasan
Date Deposited: 02 Nov 2023 05:17
Last Modified: 02 Nov 2023 05:17
URI: http://umpir.ump.edu.my/id/eprint/39155
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