Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review

Roney, Miah and Mohd Fadhlizil Fasihi, Mohd Aluwi (2024) Computational studies demonstrating dithymoquinone of Nigella sativa as a potential anti-dengue agent: Short review. Intelligent Pharmacy. pp. 1-4. ISSN 2949-866X. (In Press / Online First) (In Press / Online First)

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Abstract

Dengue is acute tropical infectious illness, which is spread by mosquitoes, has presented a significant threat to public health worldwide. Unfortunately, there are no drugs that have been clinically proven to be effective at treating or preventing dengue. The development of some drugs is significantly hampered by our incomplete understanding of dengue pathogenesis. This short review provides a brief description of potential action against DENV of dithymoquinone to develop an anti-DENV inhibitor. In-vitro, in-vivo and clinical trials are required to establish the effectiveness and safety of dithymoquinone as an anti-dengue therapy, even though computational studies have demonstrated antiviral activity against DENV.

Item Type: Article
Uncontrolled Keywords: Dengue; DENV; Anti-DENV; Nigella sativa; Dithymoquinone
Subjects: Q Science > Q Science (General)
R Medicine > RA Public aspects of medicine
T Technology > TP Chemical technology
Faculty/Division: Faculty of Industrial Sciences And Technology
Institute of Postgraduate Studies
Centre for Bioaromatic Research (Bioaromatic Centre)
Depositing User: Mrs Norsaini Abdul Samat
Date Deposited: 20 May 2024 03:54
Last Modified: 20 May 2024 03:54
URI: http://umpir.ump.edu.my/id/eprint/41275
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