Computational fluid dynamics of patient-specific coronary artery during stent treatment

Nur Syuhada, Che Amdilah and Lau, Yu Shi and Liew, Yih Miin and Wan Naimah, Wan Ab Naim and Mohd Jamil, Mohamed Mokhtarudin (2022) Computational fluid dynamics of patient-specific coronary artery during stent treatment. In: IET Conference Proceedings. IET Conference Proceedings; 2022 Engineering Technology International Conference, ETIC 2022 , 07 - 08 September 2022 , Pahang, Virtual. 216 -220., 2022 (22). ISSN 2732-4494 ISBN 978-183953782-0

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Abstract

Coronary artery disease is usually treated using stent treatment. However, restenosis is one of the major limitations of using stent. Local hemodynamics can be the main indicator of the occurrence of restenosis. In this project, a computational fluid dynamics (CFD) analysis is performed on a stented coronary artery patient with a 12-month follow-up post stent in order to determine the potential occurrence of restenosis in the patient. An OCT image of the coronary artery is taken and ethically approved from Universiti Malaya Medical Centre (UMMC). Firstly, a 3D geometry of the coronary artery will be developed using image segmentation procedure. The stent structure is smoothened within the coronary artery. Then, the geometry is meshed and CFD analysis is applied. The blood is assumed as a non-Newtonian fluid following a Carreau model of fluid viscosity. The inlet is applied with a velocity waveform, while the outlet is set as zero pressure. Lastly, the time averaged wall shear stress (TAWSS) is calculated. The region with TAWSS < 0.4 Pa is identified as a potential location for restenosis. From our simulations, the location in the middle of the stent shows TAWSS < 0.4 Pa, showing the potential of restenosis in the patient.

Item Type:	Conference or Workshop Item (Paper)
Additional Information:	Indexed by Scopus
Uncontrolled Keywords:	In-stent restenosis; Optical coherence tomography; Percutaneous coronary intervention; Wall shear stress
Subjects:	Q Science > QA Mathematics > QA75 Electronic computers. Computer science T Technology > TJ Mechanical engineering and machinery
Faculty/Division:	Institute of Postgraduate Studies College of Engineering Faculty of Manufacturing and Mechatronic Engineering Technology Centre for Research in Advanced Fluid & Processes (Fluid Centre)
Depositing User:	Mrs Norsaini Abdul Samat
Date Deposited:	17 Jul 2024 03:10
Last Modified:	17 Jul 2024 03:10
URI:	http://umpir.ump.edu.my/id/eprint/41971
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