Advancement in computational simulation and validation of congenital heart disease: A review

Ahmad Fikri Azfar, Ahmad Azaharia and Wan Naimah, Wan Ab Naim and Nor Ashikin, Md Sari and Lim, Einly and Mohd Jamil, Mohamed Mokhtarudin (2024) Advancement in computational simulation and validation of congenital heart disease: A review. Computer Methods in Biomechanics and Biomedical Engineering. pp. 1-15. ISSN 1025-5842. (In Press / Online First) (In Press / Online First)

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Abstract

The improvement in congenital heart disease (CHD) treatment and management has increased the life expectancy in infants. However, the long-term efficacy is difficult to assess and thus, computational modelling has been applied for evaluating this. Here, we provide an overview of the applications of computational modelling in CHD based on three categories; CHD involving large blood vessels only, heart chambers only, and CHD that occurs at multiple heart structures. We highlight the advancement of computational simulation of CHD that uses multiscale and multiphysics modelling to ensure a complete representation of the heart and circulation. We provide a brief future direction of computational modelling of CHD such as to include growth and remodelling, detailed conduction system, and occurrence of myocardial infarction. We also proposed validation technique using advanced three-dimensional (3D) printing and particle image velocimetry (PIV) technologies to improve the model accuracy.

Item Type:	Article
Uncontrolled Keywords:	Congenital heart disease; Computational simulation; Multiscale modelling; Multiphysics modelling
Subjects:	T Technology > TJ Mechanical engineering and machinery T Technology > TS Manufactures
Faculty/Division:	Institute of Postgraduate Studies Faculty of Manufacturing and Mechatronic Engineering Technology Centre for Research in Advanced Fluid & Processes (Fluid Centre)
Depositing User:	Mrs Norsaini Abdul Samat
Date Deposited:	17 Jul 2024 06:57
Last Modified:	17 Jul 2024 06:57
URI:	http://umpir.ump.edu.my/id/eprint/41981
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