Thanaseelan, Tanesha and Nur Aina Raihana, Muhamad Yusuff and Kutty, Rajaletchumy Veloo (2024) Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves. Malaysian Journal of Analytical Sciences, 28 (4). pp. 758-767. ISSN 1394 - 2506. (Published)
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Abstract
Plants form a natural source of key bioactive chemicals equipped with excellent antioxidant and anti-tyrosinase properties. The restorative plant Combretum indicum (C. indicum), which belongs to the Combretaceae family, was widely used in customary treatment in the past. The target of this study is to assess the effects of water as a solvent, traditional extraction strategies (maceration and Soxhlet extraction), and extraction time on C. indicum yield. The total phenolic content (TPC), as well as antioxidant and tyrosinase inhibitory activities, were observed by utilising an ultraviolet-visible spectrophotometer. DPPH radical scavenging was used to determine the antioxidant property, while a mushroom tyrosinase inhibition assay was utilised to evaluate the anti-tyrosinase activity. Maceration carried out for 72 h showed good outcomes for TPC, antioxidant, and anti-tyrosinase activities. The results showed that TPC, antioxidant assay, and anti-tyrosinase activities had a significant linear correlation (p <0.05). It is evident from the study that C. indicum leaves, which contain numerous phytochemicals, are strong antioxidants and tyrosinase inhibitors that can potentially play a significant role in the pharmaceutical and cosmetic industries.
| Item Type: | Article |
|---|---|
| Additional Information: | (Kesan Kaedah Pengekstrakan Terhadap Hasil, Jumlah Kandungan Fenolik, Sifat Antioksida, dan Anti-Tirosinase Daun Combretum indicum) |
| Uncontrolled Keywords: | antioxidant, anti-tyrosinase, Combretum indicum, maceration, Soxhlet |
| Subjects: | T Technology > TP Chemical technology |
| Faculty/Division: | Institute of Postgraduate Studies Faculty of Chemical and Process Engineering Technology |
| Depositing User: | Miss Amelia Binti Hasan |
| Date Deposited: | 05 Sep 2024 06:49 |
| Last Modified: | 05 Sep 2024 06:49 |
| URI: | http://umpir.ump.edu.my/id/eprint/42509 |
| Download Statistic: | View Download Statistics |
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