Fluid-structure interaction modelling of blood flow in peripheral arterial disease

Muhammad Firdaus, Mohd Fauzi and Nasrul Hadi, Johari and Mohd Jamil, Mohamed Mokhtarudin and Bazli, Mohd Yusoff and Guo, Baolei (2024) Fluid-structure interaction modelling of blood flow in peripheral arterial disease. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 119 (1). 117 -133. ISSN 2289-7879. (Published)

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Abstract

The study presents the fluid-structure interaction (FSI) modeling in Peripheral Arterial Disease (PAD) geometry, highlighting the effects of arterial blockage on hemodynamics and arterial wall mechanics. Employing a RANS-based SST-Tran model, the study examines stenotic PAD models under realistic boundary conditions, coupled with a hyperelastic Mooney-Rivlin model to simulate the arterial wall's response. The analysis includes velocity profiles, wall shear stress (WSS), pressure distribution, and wall displacement, revealing significant differences between healthy and stenosed models. It demonstrates adaptive hemodynamics, the impact of stenosis on flow mechanics, and potential implications for atherosclerosis and plaque formation. The findings highlight the importance of understanding stenosis severity for clinical risk assessment, treatment planning, and monitoring.

Item Type: Article
Additional Information: Indexed by Scopus
Uncontrolled Keywords: Peripheral arterial disease; Fluid-structure interaction; Atherosclerosis; Hemodynamics
Subjects: R Medicine > RS Pharmacy and materia medica
T Technology > TJ Mechanical engineering and machinery
Faculty/Division: Institute of Postgraduate Studies
Centre for Advanced Industrial Technology
Faculty of Manufacturing and Mechatronic Engineering Technology
Faculty of Mechanical and Automotive Engineering Technology
Depositing User: Mrs Norsaini Abdul Samat
Date Deposited: 17 Sep 2024 01:05
Last Modified: 17 Sep 2024 01:05
URI: http://umpir.ump.edu.my/id/eprint/42589
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