Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications

Siti Maznah, Kabeb and Nurlin, Abu Samah and Nurjannah, Salim and Farah Hanani, Zulkifli (2025) Development of bioactive patches from aloe vera and Nata De Coco for wound dressing applications. Macromolecular Symposia, 414 (1). pp. 1-6. ISSN 1521-3900. (Published)

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Abstract

This study focuses on the development and characterization of bioactive patches derived from Aloe Vera (AV) and Nata De Coco (NDC) for advanced wound dressing applications. Utilizing the solution casting method, biocomposite films are developed using polyvinyl alcohol (PVA) with varied bio-filler content (2%−10%) w/w. Fourier-transform infrared (FTIR) analysis confirms the miscibility and compatibility of PVA and bio-fillers via intermolecular hydrogen bonding. PVA/NDC10 demonstrates the highest water-holding capacity (WHC), exhibiting an increase from 157.17% (neat PVA) to 286.01%, resulting in an 82.0% enhancement. Conversely, increasing NDC content leads to a gradual decrease in tensile strength. Notably, the hybrid biocomposite film (PVA/AV/NDC) shows a significant 20.82% improvement in tensile strength, reaching 30.79 MPa. The study underscores the promise of AV and NDC bioactive patches for advanced wound dressing. Additionally, the hybrid approach shows synergistic improvements in water retention and mechanical strength, offering a comprehensive solution for effective wound management.

Item Type:	Article
Additional Information:	Indexed by Scopus
Uncontrolled Keywords:	Bioactive Patches; Aloe Vera; Nata De Coco; wound dressing
Subjects:	H Social Sciences > HD Industries. Land use. Labor T Technology > TP Chemical technology
Faculty/Division:	Faculty of Industrial Sciences And Technology Centre for Advanced Industrial Technology
Depositing User:	Dr. Siti Maznah Kabeb
Date Deposited:	01 Jul 2025 07:20
Last Modified:	01 Jul 2025 07:20
URI:	http://umpir.ump.edu.my/id/eprint/43955
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