In Vitro Study Of The Effect Of Corn Silk On Glucose Uptake By Isolated Rat Hemi-Diaphragm

Nour, A. H. and M., Ghada and Eltohami, M. S. and Mudawi, Mahmoud M. E. (2014) In Vitro Study Of The Effect Of Corn Silk On Glucose Uptake By Isolated Rat Hemi-Diaphragm. World Journal of Pharmaceutical Research (WJPR), 3 (4). pp. 2190-2195. ISSN 2277 – 7105. (Published)

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Abstract

In the present study the methanolic extract of corn silk was evaluated for antidiabetic activity. The antidiabetic activity was studied using the glucose uptake by isolated rat hemi-diaphragm using in-vitro model. Corn silk increased the uptake of glucose by isolated rat hemidiaphragm significantly (P<0.001) and was found to be more effective than insulin. It appears that corn silk has direct peripheral action on glucose uptake. The value of glucose uptake by rat hemi-diaphragm after addition of corn silk extract was 109±1 as compared to control (12± 1) and Insulin (49 ± 8)mg/g/30min .These results strongly suggest that Corn silk will be alternative choice for the treatment of diabetes mellitus.

Item Type:	Article
Additional Information:	Prof. Madya Dr. Abdurahman Hamid Nour (H.N. Abdurahman)
Uncontrolled Keywords:	Anti-diabetic; Rat hemi-diaphragm; Corn silk; Glucose uptake
Subjects:	T Technology > TP Chemical technology
Faculty/Division:	Faculty of Chemical & Natural Resources Engineering
Depositing User:	Mrs. Neng Sury Sulaiman
Date Deposited:	27 Oct 2014 06:06
Last Modified:	24 Jan 2018 03:36
URI:	http://umpir.ump.edu.my/id/eprint/6598
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