Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis

Alara, Oluwaseun Ruth and Abdurahman, N.H. and Ali, H.A. and Zain, N.M. (2021) Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis. Future Foods, 3 (100035). pp. 1-8. ISSN 2666-8335. (Published)

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Abstract

Carica papaya is a well-known plant with diverse importance to human beings. The efficacy of microwave-assisted extraction (MAE) in the recovery of phenolic compounds from C. papaya leaf was investigated in this study. The MAE process variables were optimized using response surface method; at the optimized conditions, the embedded phenolic compounds in the extract were identified through LC-QTOF-MS analysis. The results showed that the best MAE conditions were: time of irradiation at 3 min; microwave power of 420 W; feed-to-solvent ratio of 1:12 g/mL; and solvent concentration of 56% ethanol/water to achieve 102.59 mg GAE/g d.w. of total phenolic content (TPC). At these conditions, an aggregate of 72 phenolic compounds was tentatively identified. These results infer that MAE as a technique can recover phenolic compounds from C. papaya leaf. Hence, the identified compounds can further be quantified with their respective pharmacological properties in future studies.

Item Type: Article
Additional Information: Indexed by Scopus
Uncontrolled Keywords: Carica papaya leaf; Extraction; LC-QTOF-MS; Optimization; Phenolic compounds
Subjects: Q Science > QD Chemistry
T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
T Technology > TP Chemical technology
Faculty/Division: Institute of Postgraduate Studies
College of Engineering
Faculty of Chemical and Process Engineering Technology
Depositing User: Mr Muhamad Firdaus Janih@Jaini
Date Deposited: 10 Nov 2022 03:38
Last Modified: 10 Nov 2022 03:38
URI: http://umpir.ump.edu.my/id/eprint/33173
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