A review on taste masked multiparticulate dosage forms for paediatric for tenacity and toughness improvement

AL-japairai, Khater Ahmed Saeed and Hamed Almurisi, Samah and Almonem Doolaanea, Abd and Syed, Mahmood and Alheibshy, Fawaz and Alobaida, Ahmed and Nadiya, Abdul-Halim and Chatterjee, Bappaditya (2023) A review on taste masked multiparticulate dosage forms for paediatric for tenacity and toughness improvement. International Journal of Pharmaceutics, 632 (122571). pp. 1-16. ISSN 0378-5173. (Published)

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DOI/Official URL: https://doi.org/10.1016/j.ijpharm.2022.122571

Abstract

Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous contributing components such as swallowability, palatability (taste, flavour, texture, and mouthfeel), appearance, ease of administration, and patient characteristics. Multiparticulate as a dosage form is a platform technology for overcoming paediatrics' incapacity to swallow monolithic dosage forms, masking many medications' inherent nasty taste, and overcoming the obstacles of manufacturing a commercially taste masked dosage form. This review will discuss the considerations that must be taken into account to prepare taste masked multiparticulate dosage forms in the best way for paediatric use.

Item Type:	Article
Additional Information:	Indexed by Scopus
Uncontrolled Keywords:	Multiparticulate system; Paediatric; Taste masking; Unpleasant drug
Subjects:	Q Science > QD Chemistry T Technology > T Technology (General) T Technology > TA Engineering (General). Civil engineering (General) T Technology > TP Chemical technology
Faculty/Division:	Institute of Postgraduate Studies College of Engineering Faculty of Chemical and Process Engineering Technology
Depositing User:	Mr Muhamad Firdaus Janih@Jaini
Date Deposited:	31 Oct 2023 06:51
Last Modified:	31 Oct 2023 06:51
URI:	http://umpir.ump.edu.my/id/eprint/38830
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